In the fall of 2018, the European Union launched a new partnership initiative with African countries, called the Africa-Europe Alliance. It emerged as a reaction to the increasing role and weight of the African region in international relations and the intensifying struggle for its resources among global players. In this regard, the questions arise whether the developed initiative corresponds to realities of today and what objectives are being pursued. At the same time, against the backdrop of Ukraine leadership’s resolute efforts on the way to gaining full EU membership, more attention needs to be paid to the issue of cooperation between Kyiv and Brussels in the search for a cooperative approach in relations with the countries of the African continent.