The pandemic caused by COVID-19 arguably came as a shock and will have profound consequences. It has already created exceptional circumstances in NATO capitals and in other NATO structures at all levels – strategic, operational, and tactical. The objective of this article is to analyse Alliance’s reaction to the pandemic, with a focus on lessons learned and a way ahead. Bearing in mind that the Alliance has not faced a pandemic before, three following main domains should be analysed: the institutional domain (how the Alliance will adapt its activities at the strategic level), the operational domain (how NATO will adapt the Command and Control structure, plan and conduct of military exercises, and the changing business within the command structure), and the information domain (how the Alliance has been waging the information campaign in order to dispel myths and rumours/perceptions and to promote own interests and agendas for the future).