The coronavirus not only is challenging national health care systems but also creates a favourable environment for numerous information attacks. The global infodemic is another challenge to address. In the article, the author shows who benefits from spreading fakes and what goals these actors have (the most obvious actor is the Russian Federation). The article considers some fundamental principles in which an “info vaccination” may be grounded, considering national patterns of information perception. Among these principles, the following should be named: case studies of typical disinformation, mobilisation of opinion-makers for the sake of public interest, cooperation with the institutions of civil society, and, the most importantly, stressing that the public interest is the multiplied personal interest.