The role of the South Caucasus in Ukrainian foreign policy is growing. The new regional and global positioning of Azerbaijan and Georgia, as well as a new political reality in Ukraine countering the Russian aggression, have encouraged Baku, Tbilisi, and Kyiv towards mutual rapprochement in recent years. Another reason for the South Caucasus to become one of the priority dimensions for Ukrainian foreign policy is Ukraine’s interest in new international markets and its inclusion in the system of global trade routes. The aim of this article is to give a complex assessment of the current foreign policy agenda of Azerbaijan, Georgia, and Armenia for a more effective elaboration of the Ukrainian foreign policy in the region.